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November 1972

Die Hypertrophische Obstruktive Kardiomyopathie.

Arch Intern Med. 1972;130(5):799. doi:10.1001/archinte.1972.03650050117046

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Among 2,500 patients studied by cardiac catheterization in northern Germany, the authors identified 47 (approximately 2%) with hypertrophic obstructive cardiomyopathy. Strictly speaking, the authors say, that they recognize the nosologic entity of hypertrophic obstructive cardiomyopathy, but they do not believe that distinction between those with outflow obstruction and those without is warranted. Both the familial and the more frequent sporadic cases appeared in their clinical experience. The familial type showed little difference in sexual incidence, but the sporadic type showed definite male predominance (3:1).

The anatomical and clinical picture presented by German patients corresponds to that generally reported in this country. Furthermore, there was the same lack of correspondence between clinical severity and findings and as measured hemodynamically. However, in the German experience a normal electrocardiogram virtually excluded the diagnosis: signs of left ventricular hypertrophy, pathological Q waves, and repolarization abnormalities were encountered frequently but in varying combinations in different

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