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December 1972

Longitudinal Studies of Lipoid Nephrosis

Author Affiliations


From the Department of Clinical Medicine (Drs. Ooi, Chen, and Khoo), University of Singapore and the Department of Pathology (Dr. Tan), Outram Road General Hospital, Singapore.

Arch Intern Med. 1972;130(6):883-886. doi:10.1001/archinte.1972.03650060073012

An 11-year study of 33 patients with lipoid nephrosis treated with a low-dosage prednisolone regime is presented. At the final evaluation 19 patients were in complete remission, 3 in incomplete remission, and 8 had not responded. There were two renal deaths and one nonrenal death. Cyclophosphamide therapy produced a complete remission in four of six patients who did not respond to steroid therapy. Progression of lipoid nephrosis into renal insufficiency was observed in four patients.

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