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April 1973

Resistance to Trauma.

Author Affiliations

Charleston, SC

Arch Intern Med. 1973;131(4):618. doi:10.1001/archinte.1973.00320100146045

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This book is another in the Living Chemistry series which the editor states was conceived "to advance the newer knowledge of chemical medicine in the cause of clinical practice." Hruza, who has had extensive experience in the study of adaptation to trauma utilizing the Noble-Collip drum (and other techniques to a lesser extent) has presented the available information on adaptation to mechanical trauma in a rather thorough manner. Some background information is initially presented on the etiology and physiologic changes occurring in shock in general; then the reader is presented with extremely short chapters of one to two pages which deal with the experimental data that has been collected in studies on the development of resistance to mechanical trauma. This includes the response of various organ systems (including central nervous system, adrenal glands, and circulatory system) and metabolic responses and cross-resistance between mechanical trauma, endotoxin trauma, tourniquet trauma, and epinephrine

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