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May 1973

Parathyroid Localization Using Venous Catheterization and Radioimmunoassay

Author Affiliations


From the departments of surgery (Drs. Cope and Wang), medicine (Drs. Powell, Murray, and Potts), and radiology (Dr. Pollard), Harvard Medical School and the Massachusetts General Hospital, Boston. Dr. Powell is now at the Department of Biochemistry, Trinity College, Dublin, and Dr. Murray is at the Department of Medicine, University of Toronto, Toronto.

Arch Intern Med. 1973;131(5):645-648. doi:10.1001/archinte.1973.00320110029003

Radioimmunoassay of parathyroid hormone contained in venous catheter samples from the major veins of the neck and thorax in patients with primary hyperparathyroidism has permitted preoperative localization of the source of excess hormone secretion in 28 (56%) of 50 patients. Results show that the technique has many advantages over other methods for preoperative parathyroid localization.