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May 1973

Renal Failure and Transient Paraproteinemia Due to Leptospira pomona: Case Reports and Literature Review

Author Affiliations

Woolloongabba, Queensland, Australia

From the Renal Unit, Princess Alexandra Hospital, Woolloongabba, Queensland, Australia. Dr. Bain is now with the Department of Haematology, Hammersmith Hospital, London.

Arch Intern Med. 1973;131(5):740-745. doi:10.1001/archinte.1973.00320110124020

Two patients developed acute renal failure with Leptospira pomona infection. In both patients the oliguria persisted for two weeks. Renal biopsies showed a marked focal mononuclear infiltrate. One patient appears to have made an uninterrupted recovery. The other patient has developed interstitial fibrosis and impairment of renal function. In one patient an abnormal band composed of IgM appeared in the γ-globulin area. This persisted for three weeks.

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