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October 1973

A New Method for the Diagnosis of Systemic Amyloidosis

Author Affiliations

Uppsala, Sweden

From the departments of pathology (Dr. Westermark) and clinical cytology (Dr. Stenkvist), University of Uppsala, Sweden.

Arch Intern Med. 1973;132(4):522-523. doi:10.1001/archinte.1973.03650100040007

Twenty-eight patients were clinically suspected of secondary amyloidosis; eight of them had abnormal results from fine-needle biopsy of subcutaneous abdominal fat. The abnormal results were later confirmed after rectal biopsy or autopsy. In addition, seven of the 19 patients with normal results also had normal results from rectal biopsies. Fine-needle biopsy of subcutaneous fat is a simple and reliable method for diagnosing secondary systemic amyloidosis.

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