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December 1973

Erythrocytosis After Renal Transplantation: Its Occurrence in Two Recipients of Kidneys From the Same Cadaveric Donor

Author Affiliations

Iowa City; Chicago; Iowa City

From the divisions of hematology-oncology (Drs. Wu and DeGowin) and nephrology (Drs. Gibson and Freeman), Department of Medicine, and the Department of Urology (Dr. Bonney), University of Iowa Hospitals and Veterans Administration Hospital, Iowa City, and the Section of Hematology, Department of Medicine, University of Illinois Medical Center, Chicago (Dr. Fried). Dr. Gibson is now at Walter Reed Hospital, Washington, DC.

Arch Intern Med. 1973;132(6):898-902. doi:10.1001/archinte.1973.03650120096018

Since anemia is one of the main obstacles to optimal rehabilitation of anephric patients supported with hemodialysis, it is ironic that erythrocytosis has proved a troublesome complication in a few patients who have undergone renal transplantation. This complication was first described by Nies et al1 and subsequently confirmed by Hoffman,2 Jepson et al,3 Swales and Evans,4 Westerman et al,5 Abbrecht and Greene,6 and Denny et al.7 The purpose of this report is to describe two patients who developed erythrocytosis after each received a transplanted kidney from the same cadaveric donor. We will compare their clinical manifestations and erythropoietin levels with those reported in the literature in an effort to understand the pathogenesis of the plethora.

Patient Summaries 

Patient 1.  —A 29-year-old graduate student from Bolivia was first admitted to the University of Iowa Hospitals on July 15, 1969, for treatment of uremia.

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