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February 1974

Management of Patients for Radical Cancer Surgery.

Arch Intern Med. 1974;133(2):325. doi:10.1001/archinte.1974.00320140163038

This article is only available in the PDF format. Download the PDF to view the article, as well as its associated figures and tables.


This small text, which is written and edited by a group of clinical anesthesiologists, is well done. It contains a tremendous amount of valuable information for the clinical anesthesiologist and the practicing surgeon. The chapters are devoted to some of the major physiologic alterations occurring in association with any major surgical illness, including problems in blood coagulation, physiology and biochemistry of hemorrhagic shock, an excellent discussion of the oxygen dissociation curve and its alteration by multiple transfusions, the influence of 2-3 diphosphoglyceride (DPG), complications associated with prolonged operation and anesthesia, and the body fluid shifts associated with any major surgery.

To those who may not be familiar with the problem, the illustrations of the detritus that is collected on presently available efficient blood filters is quite illuminating. The chapters dealing with hemorrhagic shock, septic shock, and oxygen dissociation curve review the biochemistry of aerobic and anaerobic metabolism and the

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