The size of the liver and spleen was determined by scintiphotography in 214 patients and the results correlated with the physical findings concerning these two organs. False-positive interpretations of liver size and false-negative interpretations of spleen size were very common as determined by physical examination. The findings of a palpable spleen by physical examination correlated to a very high degree with anatomical enlargement of that organ.
Halpern S, Coel M, Ashburn W, et al. Correlation of Liver and Spleen Size: Determinations by Nuclear Medicine Studies and Physical Examination. Arch Intern Med. 1974;134(1):123–124. doi:10.1001/archinte.1974.00320190125018
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