From 1957 to 1972, 114 cases of primary hypothyroidism were found in 60,073 patients seen at the Joslin Clinic, Boston (incidence, 0.19%). In 94 patients, the diabetes mellitus preceded the hypothyroidism. In 38% of the diabetic patients who eventually became hypothyroid, the diabetes mellitus was noted before the age of 30 years. The elapsed time between the diagnosis of the
Ganz K, Kozak GP. Diabetes Mellitus and Primary Hypothyroidism. Arch Intern Med. 1974;134(3):430–432. doi:10.1001/archinte.1974.00320210040005
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