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October 1974

Acute Iodide Intoxication With Cardiac Irritability

Author Affiliations

From the Department of Medicine, Cardiovascular Section, The Medical College of Wisconsin and Milwaukee County General Hospital, Milwaukee.

Arch Intern Med. 1974;134(4):760-762. doi:10.1001/archinte.1974.00320220162024

The common manifestations of acute iodide intoxication include skin eruptions, fever, coryza, conjunctivitis, and lymphadenopathy. Rarely have parotid swelling and myxedema occurred.1 The following report describes iodide intoxication with cardiac irritability as one of the major manifestations.

Patient Summary  A 54-year-old black, male, custodial worker was admitted to Milwaukee County General Hospital on Feb 27, 1972, because of acute iodide intoxication and considerable ventricular irritability. About 18 hours previously, while at his aunt's home, he had inadvertently consumed approximately 600 ml of a potassium iodide solution containing 15 gm of iodide. The solution was a "home preparation" of saturated potassium iodide in water used by the patient's aunt for "rheumatism". Being clear and stored in a quart bottle in the refrigerator, the solution was mistaken by the patient for ice water. In the next 12 hours following the ingestion, he noted progressive swelling of the face, neck, and mouth