Neurologic complications occur in 20% to 30% of patients with bacterial endocarditis.1-5 These complications include ischemic lesions resulting in focal neurologic signs, abscess formation, meningeal reaction, and formation of cerebral mycotic aneurysm—with or without intracranial hemorrhage. Cerebrovascular lesions occur in approximately 50% of patients in this group.1,2 The frequency of subarachnoid hemorrhage (SAH) secondary to ruptured mycotic aneurysm in several large series appears to vary between 2.6% and 8%.6,7 The incidence of clinically apparent mycotic aneurysm in patients with bacterial endocarditis varies between 2% and 10%.1,2,6,8 9 Perhaps because of the low incidence of this entity and because the initial sign is often a catastrophic, fatal SAH, the pathogenesis and natural history of mycotic aneurysm are not as well known as other types of intracranial aneurysms. Recent experience with a patient with subacute bacterial endocarditis coupled with a unique evolution of angiographie findings provoked a reconsideration
Katz RI, Goldberg HI, Selzer ME. Mycotic Aneurysm: Case Report With Novel Sequential Angiographic Findings. Arch Intern Med. 1974;134(5):939–942. doi:10.1001/archinte.1974.00320230149027
Monkeypox Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.