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This is an excellent monograph in which the senior author-editor achieves his primary aim (as stated in the preface) of providing newer information and concepts as well as of emphasizing older valuable landmarks. The seven chapters are written by the two authors-editors and other authorities in the field and deal with the following topics: pathology of multiple myeloma, the myeloma cell, experimental plasma cell tumors, antigen binding M-components, benign monoclonal gammopathies, immunologic deficiency syndromes, and amyloidosis. In putting together the conceptual design of each chapter, the authors draw on their own vast experience, particularly where necessary to fill in gaps in knowledge. The various authors do not hesitate to go to the edge of current knowledge to provide useful concepts regarding the unknown, tentative though they must be. Another advantage is the relating of concepts of mechanisms involved in myeloma and similar disorders to other phenomena, such as autoimmunity, cancer,