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March 1976

Fever of Unknown Origin Secondary to Brewer's Yeast Ingestion

Author Affiliations

From the Division of Pulmonary Medicine, Department of Medicine, University of Missouri Medical Center, and the Veterans Administration Hospital, Columbia, Mo.

Arch Intern Med. 1976;136(3):332-333. doi:10.1001/archinte.1976.03630030064011

The interest in nutrition has brought about the proliferation of "health food" stores. Among the nutritional supplements offered by these establishments are those that contain viable microorganisms, specifically, unpasteurized yogurt and brewer's yeast powder or tablets. We report a patient who we believe demonstrates the potential problems that may occur secondary to ingestion of these organisms.

PATIENT SUMMARY  A 68-year-old man was in good health until May 28, 1974, when he noted malaise, fever, diaphoresis, and nausea. These symptoms persisted and were accompanied by night sweats. He was admitted to Laughlin Hospital on June 1. Physical examination results were within normal limits. Initial laboratory data was unremarkable, except for an erythrocyte sedimentation rate (ESR) of 28 mm/hr and a serum glutamic oxaloacetic transaminase (SGOT) value of 55 units. Contrast studies of the bowel and gallbladder showed only irritation of the duodenal cap and a few diverticula in the proximal colon. The

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