Familial Mediterranean fever (FMF) affects the inhabitants of the Mediterranean littoral and the adjacent areas. In 70% of the cases, FMF results in renal failure, usually in the third or fourth decade, that is caused by renal amyloid deposition with relative sparing of other organs.1,2 In Israel, amyloid attributable to FMF is a major cause of renal failure, and, although at least one case of renal homotransplantation has been recorded in detail,3 there has been no record of the treatment of renal failure by regular hemodialysis in a series of patients with amyloidosis of FMF. In the past five years, we have used regular hemodialysis to treat ten patients who had renal failure caused by amyloidosis of FMF. We found that dialysis produced acceptable results, and that it may prolong comfortable life for years.
SUBJECTS AND METHODS
The ten patients who had FMF were Israeli Jews of Sephardic
Ari JB, Zlotnik M, Oren A, Berlyne GM. Dialysis in Renal Failure Caused by Amyloidosis of Familial Mediterranean Fever: A Report of Ten Cases. Arch Intern Med. 1976;136(4):449–451. doi:10.1001/archinte.1976.03630040051011
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