Goodpasture syndrome, the association of pulmonary hemorrhage with antiglomerular basement membrane (anti-GBM)-mediated proliferative glomerulonephritis, usually results in irreversible renal failure. Patients who survive without chronic hemodialysis or renal homotransplantation have rarely had severe renal involvement. We describe a patient whose condition improved after an episode of acute renal failure.
A 22-year-old white woman was admitted to the University Hospitals on March 10, 1972, with a three-hour history of cough, blood-tinged sputum, and shortness of breath. She had been in excellent health, except for a two-day episode of rhinitis and headache one week before admission. She denied chills, fever, sputum production, or previous pulmonary or cardiovascular complaints. She had been treated for a urinary tract infection with antibiotics at 11 years of age. Four years before admission, she was given birth control pills because of heavy menstrual flow. Her hematocrit value had been 41% in November 1969 during a routine
Cohen LH, Wilson CB, Freeman RM. Goodpasture Syndrome: Recovery After Severe Renal Insufficiency. Arch Intern Med. 1976;136(7):835–837. doi:10.1001/archinte.1976.03630070073021
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