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September 1976

Secondary Pituitary Insufficiency: Report of Three Cases of Ectopia or Hemiagenesis of the Thyroid Gland

Author Affiliations

From the departments of endocrinology (Drs Leiba and Ber) and medicine (Drs Zahavi and Samuel), Beilinson Medical Center, Petah Tikva, Israel, and the departments of internal medicine (Dr Shani) and nuclear medicine (Ms Borohowsky), Sheba Medical Center, Ramat Gan, Israel. Both institutions are affiliated with Tel Aviv University Medical School.

Arch Intern Med. 1976;136(9):1010-1015. doi:10.1001/archinte.1976.03630090040010

Three patients with clinical and laboratory manifestations suggestive of pituitary insufficiency due to the presence of a pituitary tumor were found to have longstanding myxedema. The insidious appearance of the signs of hypothyroidism was explained by the cause of their disease—an ectopic thyroid gland in two patients and hemiagenesis of the thyroid in the third. Early recognition and treatment of such cases is important.

(Arch Intern Med 136:1010-1015, 1976)

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