A 43-year-old woman had diabetes insipidus and amenorrhea. There was panhypopituitarism on endocrine testing and visual field examination showed inexorably progressive loss to bitemporal hemianopsia. All radiographic findings were normal, but craniotomy disclosed the cause of this chiasmal syndrome to be an intrasellar abscess which, on culture, grew a Gram-positive anaerobe, Peptococcus. Intrasellar or pituitary abscess is rare, but it must always be considered in the differential diagnosis of the chiasmal syndrome, since loss of pituitary and visual function may occur much more rapidly than with the tumors most often responsible for this syndrome and since surgical cure is possible.
(Arch Intern Med 136:1041-1043, 1976)
Neelon FA, Mahaley MS. Chiasmal Syndrome Due to Intrasellar Abscess. Arch Intern Med. 1976;136(9):1041–1043. doi:10.1001/archinte.1976.03630090063015
Monkeypox Resource Center
Customize your JAMA Network experience by selecting one or more topics from the list below.