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October 1976

Hemodialysis in Diabetics: Complications in Insulin-Dependent Patients Accepted for Renal Transplantation

Author Affiliations

From the Division of Nephrology, departments of medicine and surgery, University of Minnesota Hospitals, Minneapolis.

Arch Intern Med. 1976;136(10):1126-1130. doi:10.1001/archinte.1976.03630100038011

The hemodialysis complications in 67 insulin-dependent diabetic patients accepted for renal transplantation were compared with those in 67 nondiabetic hemodialysis patients. Eleven of the 67 diabetic patients died before receiving a renal transplant—four of myocardial infarction, three of dialysis-related causes, and four of infections. One of the 67 nondiabetic patients died of infection before transplantation. The diabetic patients experienced more complications on dialysis than did the nondiabetic patients; they were more hypertensive and required more ultrafiltration during dialysis. In addition, the diabetic patients had a higher incidence of hypertensive episodes during dialysis, as well as a high incidence of predialysis hyperglycemia. These findings suggest that diabetic patients with renal failure should be dialyzed more frequently and transplanted as soon as possible in order to decrease the complications associated with hemodialysis.

(Arch Intern Med 136:1126-1130, 1976)

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