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October 1976

Bone-Marrow Imaging in Pure Red Blood Cell Aplasia

Author Affiliations

From the departments of medicine (Drs Bunn and Rosenthal) and radiology (Dr McNeil), Peter Bent Brigham Hospital, Harvard Medical School, Boston, and the Department of Medicine, Veterans Administration Hospital, Vanderbilt University, Nashville, Tenn (Dr Krantz).

Arch Intern Med. 1976;136(10):1169-1172. doi:10.1001/archinte.1976.03630100081021

Bone-marrow scintigraphy with indium chloride In 111 was performed on a patient with pure red blood cell aplasia before and after successful treatment with immunosuppressive drugs. The return of erythroid precursors to the bone marrow was accompanied by a substantial increase in the marrow uptake of111In. The distribution of111In in the posttreatment scan was indistinguishable from that of52Fe. These results indicate that indium chloride In 111 is a useful agent for the delineation of erythroid cellularity within bone marrow.

(Arch Intern Med 136:1169-1172, 1976)