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November 1976

Segmental Renin Sampling and Partial Nephrectomy in Renal Hypertension

Author Affiliations

From the Ewen Downie Metabolic Unit and the Departments of Radiology, Urology, and Nuclear Medicine, Alfred Hospital, Melbourne, Australia.

Arch Intern Med. 1976;136(11):1297-1298. doi:10.1001/archinte.1976.03630110059015

Selective renin sampling from renal vein tributaries identified a high-renin source in the lower pole of the left kidney in a 16-year-old boy who had gradually developed hypertension after blunt left renal trauma. Localized renin secretion from the ischemic pole was associated with suppression of renin secretion from both the contralateral kidney and the normal part of the affected kidney. Removal of ischemic tissue by partial nephrectomy produced sustained correction of hypertension. The findings indicate that segmental renin sampling can define indications for partial nephrectomy in renal hypertension.

(Arch Intern Med 136:1297-1298, 1976)

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