Gallium citrate Ga 67 (67Ga) scans were performed in 50 consecutive lymphoma patients who underwent routine staging. The overall accuracy of67Ga scans was greater than 80% for all nodal sites except the spleen (63%). Sensitivity was greater than 88% in the neck and mediastinum, 67% in the abdomen-pelvis, and 33% for the spleen. Specificity was greater than 85% for all nodal sites except for the mediastinum (67%). The accuracy of pedal lymphangiograms was 75%, sensitivity 87%, and specificity 68%. Gallium 67 scans complemented the lymphogram in the abdomen-pelvis but, due to limited sensitivity and high number of equivocal studies (16%), did not replace it. Infraclavicular, pectoral, and mediastinal lesions were detected by67Ga scans when missed by other means. In 20% to 25% of patients,47Ga scans provided information not afforded by other diagnostic studies and are therefore considered an important staging procedure for lymphoma patients.
(Arch Intern Med 136:1370-1374, 1976)
Seabold JE, Votaw ML, Keyes JW, Foley WD, Balachandran S, Gill SP. Gallium Citrate Ga 67 Scanning: Clinical Usefulness in Lymphoma Patients. Arch Intern Med. 1976;136(12):1370–1374. doi:10.1001/archinte.1976.03630120022010
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