Detailed hemodynamic, metabolic and blood volume studies were performed in a patient with hydatidiform mole who developed pulmonary edema associated with a high cardiac output. Several factors including hyperthyroidism, hypervolemia, and the molar state probably contributed to the left ventricular failure in this patient. Results of these studies suggest that patients with hydatidiform mole and pulmonary edema need correction of the hypervolemia as well as removal of the molar tissue.
(Arch Intern Med 137:367-369, 1977)