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Article
May 1977

Anemia in Primary Hyperparathyroidism

Author Affiliations

From the Departments of Medicine (Drs Boxer and Ellman), Pathology (Dr Geller), and Surgery (Dr Wang), Massachusetts General Hospital, Boston.

Arch Intern Med. 1977;137(5):588-590. doi:10.1001/archinte.1977.03630170020008
Abstract

Although anemia has not been widely appreciated as a complication of primary hyperparathyroidism, 5.1% of the individuals with this disorder seen at the Massachusetts General Hospital since 1962 had a normochromic, normocytic anemia that could not be related to blood loss, a deficiency state, or uremia. The anemic group had more advanced bone disease and higher levels of serum calcium, alkaline phosphatase, and parathyroid hormone than the nonanemic group. Results of bone marrow biopsies performed in five patients showed variable degrees of myelofibrosis. However, none of the patients had hepatosplenomegaly, a myelophthisic peripheral blood smear, leukopenia, or thrombocytopenia. Removal of the abnormal parathyroid glands led to improvement or correction of the anemia.

(Arch Intern Med 137:588-590, 1977)

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