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June 1977

Hepatic Necrobacillosis: Report of a Case Resembling Metastatic Tumor

Author Affiliations

From the Departments of Medicine (Drs Young and Harper) and Pathology (Dr Taylor), William Beaumont Army Medical Center, El Paso, Tex. Dr Young is now with the Department of Medicine, Veterans Administration Hospital, Houston. Dr Harper is now with the Walter Reed Army Medical Center, Washington, DC. Dr Taylor is now with the Peninsula General Hospital, Salisbury, Md.

Arch Intern Med. 1977;137(6):804-807. doi:10.1001/archinte.1977.03630180076022

A 47-year-old man had multiple pyogenic liver abscesses from which the anaerobic bacteria Fusobacterium nucleatum and Peptostreptococcus were isolated. The clinical course, diagnostic evaluation, and appearance of the lesions at surgery suggested metastatic tumor. Histologically, the lesions consisted of necrotic liver tissue surrounded by zones of acute and chronic inflammation and fibrous connective tissue closely resembling the lesions of hepatic necrobacillosis attributable to F necrophorum. Treatment with high doses of penicillin was curative.

(Arch Intern Med 137:804-807, 1977)

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