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June 1977

Use of Anticoagulants in the Treatment of Ischemic Heart Disease

Arch Intern Med. 1977;137(6):813. doi:10.1001/archinte.1977.03630180085031

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To the Editor.—  I read with interest the two articles in the November 1976 issue of the Archives relating to the use of anticoagulants in the treatment of ischemic heart disease. In their communication, Drs Rogel and Bassan (136:1229-1230, 1976) criticized the previously published papers advocating the "reopening of the anticoagulant issue" for several reasons. They stated that "the large majority of patients were not treated in university or university-affiliated hospitals." This statement implies that valid studies cannot be done in nonuniversity-affiliated hospitals. I resent this implication and believe that the authors cannot support it with any kind of controlled study or statistically valid data. Their other criticisms of these studies as being retrospectively performed and uncontrolled are valid, and their criticism of them should rest on this basis and not on the type of hospital in which they were performed.Incidentally, I have not administered anticoagulant drugs on a

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