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July 1977

Aspergillus terreus Osteomyelitis

Arch Intern Med. 1977;137(7):918-920. doi:10.1001/archinte.1977.03630190072018

Aspergillus terreus infection limited to the L1-2 disk space and first and second lumbar vertebrae developed in a patient not predisposed to invasive aspergillosis. The observation of morphologically distinct secondary spores (aleuriospores) on microscopic examination of open biopsy specimens permitted a preliminary identification of A terreus, which was confirmed by culture. The infection was eradicated with amphotericin B in a total dose of 3 gm. Aspergillus terreus is usually a saprophyte. The present case and four others collected from the literature establish this species as an invasive pathogen.

(Arch Intern Med. 137:918-920, 1977)