We describe here a family with hemolytic-uremic syndrome culminating in renal failure and severe hypertension in the involved male adults. Members of this family developed a microangiopathic hemolytic anemia, progressive renal failure, the onset of elevation of blood pressure, and an untimely death in young adulthood. One affected family member has survived the initial crisis. The family history presents further evidence for an autosomal dominant pattern of inheritance of hemolytic-uremic syndrome with presentation in adulthood.
(Arch Intern Med 137:1155-1157, 1977)
Karlsberg RP, Lacher JW, Bartecchi CE. Adult Hemolytic-Uremic Syndrome: Familial Variant. Arch Intern Med. 1977;137(9):1155–1157. doi:10.1001/archinte.1977.03630210037011
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