In this issue of the Archives (p 628) Heath et al describe a patient in whom cerebral abscesses were eventually documented by computerized tomography (CT). Using this technique, which has been thoroughly described in the literature, they at first did not diagnose the lesion, then later they did identify at least one abscess after the patient had been injected with a large volume of iodinated radiographic contrast medium. This technique, dubbed "computed angiotomography" by Ethier,1 its earliest advocate, but now referred to as contrast-enhanced computerized tomography, has increased the sensitivity and specificity of CT scanning. The injected iodine, which is highly absorbent for x-rays in the diagnostic energy range, may be identified as it circulates in large blood pools, such as aneurysms, arteriovenous malformations, and some brain tumors, or in other lesions where it has accumulated after escaping through the damaged blood brain barrier.
Computerized tomographic scans of the
Davis DO. Contrast-Enhanced Computerized Tomography. Arch Intern Med. 1978;138(4):530–531. doi:10.1001/archinte.1978.03630280012008
Customize your JAMA Network experience by selecting one or more topics from the list below.