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June 1978

Hypertension Following Renal Transplantation

Author Affiliations

The Cleveland Clinic Foundation 9500 Euclid Ave Cleveland, OH 44106

Arch Intern Med. 1978;138(6):906-907. doi:10.1001/archinte.1978.03630310006005

The remission of hypertension following renal transplantation in man has been well documented1 and is widely known. Less familiar perhaps to the internist and practitioner is the astonishingly high incidence of hypertension recurring in the second or third month following the transplant. A rapid review of the results of four recent studies that involved a total of 316 patients showed that blood pressure rose to hypertensive levels (diastolic pressure > 100 mm Hg) in about half of the subjects.2-5 Serial observations from different centers agree that in patients who were hypertensive before transplantation, the elevated blood pressure often remits following a successful transplantation; only 8% to 17% are hypertensive during the first one or two months following surgery. However, the incidence of hypertension then climbs steadily to plateau at about 50% to 60%; in one series, as many as 85% of patients became hypertensive at one time or