[Skip to Content]
[Skip to Content Landing]
July 1978

Cryoglobulinemia and Amyloidosis Associated With Intestinal Lymphoma

Arch Intern Med. 1978;138(7):1158-1160. doi:10.1001/archinte.1978.03630320090034

A case of lymphocytic lymphoma of the small intestine was associated with cryoglobulinemia and amyloidosis. The neoplastic lymphoid cell demonstrated surface IgG membrane markers by immunofluorescence and immunoelectron microscopy. The cryoglobulins were characterized as monoclonal IgG3 proteins with λ light chains. Amyloidosis of the small intestine and regional lymph nodes was found in association with lymphatic infiltration of these organs, suggesting the production of amyloid in situ.

(Arch Intern Med 138:1158-1160, 1978)