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October 1978

Bone Marrow Necrosis: Acute Microcirculation Failure in Myelomonocytic Leukemia

Author Affiliations

From the Hematology Service (Drs Bernard, Oberling, and Boilletot) and the Laboratory of Normal Anatomy (Dr Sick), Centre Hospitalier Universitaire; and the Electron Microscopy and Experimental Hematology Laboratory, Blood Transfusion Center (Dr Oberling), Strasbourg.

Arch Intern Med. 1978;138(10):1567-1569. doi:10.1001/archinte.1978.03630350089025

We saw bone marrow necrosis in a case of acute myelomonocytic leukemia. The diagnosis was made during the patient's life, and the bone marrow microcirculation was studied immediately postmortem. Histology and injection of the bone marrow arteries showed an acute microcirculation failure.

The pathogenesis and possible relationship with soluble immune complexes was studied.

(Arch Intern Med 138:1567-1569, 1978)