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May 1979

Nephropathy With Behçet's Syndrome

Arch Intern Med. 1979;139(5):602-603. doi:10.1001/archinte.1979.03630420088030

To the Editor.—  In an article in the Archives concerning Behçet's syndrome (138:1122-1124, 1978), it was noted that a substantial number of patients with this syndrome have a discrete urinary abnormality, consisting of proteinuria or microhematuria, or both. Although renal amyloidosis has previously been reported in Behçet's syndrome, the article by Rosenthal et al suggests that the abnormal sediment that was seen in their cases may represent a benign renal lesion without any amyloid deposition.1Nephropathy with Behçet's syndrome has been thought to be very unusual. We have recently described a patient with renal failure secondary to interstitial nephritis in whom Behçet's syndrome developed during the course of her nephropathy.2 In addition, Cansu et al3 have described a case of Behçet's syndrome associated with proliferative necrotizing glomerulonephritis with crescent formation. These reports suggest that nephropathy associated with Behçet's syndrome may not be as rare as was once