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February 1980

Echocardiographic Systolic Time Intervals: Left Ventricular Performance in Coronary Artery Disease

Author Affiliations


From the Department of Cardiology, Division of Medicine, Wilford Hall USAF Medical Center, Lackland AFB, Tex (Drs Chilton, Oliveros, Stutts, Beckmann, and Boucher). Dr Boucher is now with the Cardiac Unit, Massachusetts General Hospital, Boston.

Arch Intern Med. 1980;140(2):240-243. doi:10.1001/archinte.1980.00330140098025

• The ratio of the preelection period to the left ventricular ejection time (PEP/LVET), obtained from the aortic root echocardiogram, was studied immediately before and after left ventricular (LV) cineangiography in 23 patients with documented coronary artery disease. The initial PEP/LVET ratio was inversely related to LV ejection fraction (r = —.78, P ≤.001). Repeat measurements taken 60 s after angiography showed a significant decrease from a mean value of.36 ±.13 to.27 ±.08 (P ≤.005). Furthermore, when patients were divided into those with an initial PEP/LVET value above and below 0.40, those with a higher value showed a significantly greater decrease following contrast left ventriculography (mean decrease, 0.16 vs 0.06, P ≤.01). This study indicates that systolic time intervals derived from echocardiography are a reliable noninvasive measure of LV function, and that ventricular function improves following left ventriculography, with the degree of improvement being inversely related to initial function.

(Arch Intern Med 140:240-243, 1980)