• The ratio of the preelection period to the left ventricular ejection time (PEP/LVET), obtained from the aortic root echocardiogram, was studied immediately before and after left ventricular (LV) cineangiography in 23 patients with documented coronary artery disease. The initial PEP/LVET ratio was inversely related to LV ejection fraction (r = —.78, P ≤.001). Repeat measurements taken 60 s after angiography showed a significant decrease from a mean value of.36 ±.13 to.27 ±.08 (P ≤.005). Furthermore, when patients were divided into those with an initial PEP/LVET value above and below 0.40, those with a higher value showed a significantly greater decrease following contrast left ventriculography (mean decrease, 0.16 vs 0.06, P ≤.01). This study indicates that systolic time intervals derived from echocardiography are a reliable noninvasive measure of LV function, and that ventricular function improves following left ventriculography, with the degree of improvement being inversely related to initial function.
(Arch Intern Med 140:240-243, 1980)
Chilton RJ, Oliveros RA, Stutts BS, Beckmann CH, Boucher CA. Echocardiographic Systolic Time Intervals: Left Ventricular Performance in Coronary Artery Disease. Arch Intern Med. 1980;140(2):240–243. doi:10.1001/archinte.1980.00330140098025
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