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August 1980

Renal Parenchymal Malakoplakia: A Case Associated With Renal Vein Thrombosis and Partial Recovery of Kidney Function

Author Affiliations

From the Departments of Medicine (Drs Garcia-Garcia, Hong, and Pollak) and Pathology (Dr Weiss), University of Cincinnati Medical Center.

Arch Intern Med. 1980;140(8):1111-1114. doi:10.1001/archinte.1980.00330190123041

• A 65-year-old woman with bilateral renal parenchymal malakoplakia and renal vein thrombosis had severe azotemia, bilaterally enlarged kidneys, urinary tract infection, and sepsis. Angiographic studies demonstrated left renal vein thrombosis. A percutaneous kidney biopsy specimen showed the characteristic Michaelis-Gutmann bodies. After therapy with fluid replacement, antibiotics, and long-term anticoagulation, kidney function improved and both kidneys decreased in size. We suggest that, with adequate treatment of urinary tract infection and correction of potential insults to the kidney, progression of this peculiar disease can be prevented.

(Arch Intern Med 140:1111-1114, 1980)

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