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November 1980

Saccharomyces cerevisiae Septicemia

Author Affiliations

From the Section of Infectious Diseases, Department of Medicine, Louisiana State University Medical Center and the Veterans Administration Medical Center, Shreveport.

Arch Intern Med. 1980;140(11):1539. doi:10.1001/archinte.1980.00330220085032

• We report the first known case of septicemia caused by Saccharomyces cerevisiae. It occurred nosocomially in a hyperalimented burned man. It is a rare example of disease caused by S cerevisiae, which, like many saprophytes, can become pathogenic in the debilitated. The case is remarkable for its apparent origin in a bleeding esophageal lesion, for its clinical character istics, including profound neutropenia, thrombocytopenia, hypothermia, and monocytopenia, and for its cure by amphotericin B.

(Arch Intern Med 140:1539, 1980)