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January 1981

Familial Association of Giant Cell Arteritis: A Case Report and Brief Review

Author Affiliations

From the Department of Medicine, The Johns Hopkins Hospital, Baltimore.

Arch Intern Med. 1981;141(1):115-117. doi:10.1001/archinte.1981.00340010107022

The initial report of a father-daughter pair with giant cell arteritis (GCA) is made. To our knowledge, it represents only the 12th known familial aggregation of polymyalgia rheumatica (PMR) and/or GCA. This provides evidence for direct transmission of GCA during two generations and helps to establish a genetic mode of inheritance for this disease. Clinically, the familial and nonfamilial forms of PMR and/or GCA are indistinguishable.

(Arch Intern Med 141:115-117, 1980)