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June 1981

Treatment of Massive Phenobarbital Overdose With Dopamine Diuresis

Arch Intern Med. 1981;141(7):938-940. doi:10.1001/archinte.1981.00340070118025

• We report a case of severe phenobarbital sodium overdose with a peak plasma concentration of 253 μg/mL, normally considered fatal. The patient was successfully treated with forced alkaline diuresis. Treatment was unusual in that dopamine hydrochloride was used to sustain the diuresis.

(Arch Intern Med 1981;141:938-940)