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Clinical Observation
February 1982

Spontaneous Regression of a Postpartum Pituitary Mass Demonstrated by Computed Tomography

Author Affiliations

From the Departments of Medicine (Drs Zeller, Cerletty, and Rabinovitch) and Radiology (Dr Daniels), Milwaukee County Medical Complex and the Medical College of Wisconsin, Milwaukee.

Arch Intern Med. 1982;142(2):373-374. doi:10.1001/archinte.1982.00340150173029

• An 18-year-old woman had postpartum thyrotoxicosis, hypercalcemia, and secondary adrenocortical insufficiency. A pituitary mass with suprasellar extension was demonstrated on computed axial tomography (CT). The patient subsequently became hypothyroid and normocalcemic, and repeated CT scanning showed that the pituitary mass had undergone a spontaneous regression in size. Computed axial tomographic scanning is an important modality for the evaluation of postpartum pituitary masses and their natural history. This case suggests that some patients with postpartum hypopituitarism and a pituitary mass need not have early surgical intervention but may be closely observed and treated by hormone replacement alone.

(Arch Intern Med 1982;142:373-374)