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March 1982

Bone Marrow Phagocytosis in Sarcoidosis

Author Affiliations

From the Hematology-Oncology Service, Walter Reed Army Medical Center, Washington, DC (Dr Taylor); and the Department of Medicine, Uniformed Services University of the Health Sciences, Bethesda, Md (Dr Berenberg).

Arch Intern Med. 1982;142(3):479-480. doi:10.1001/archinte.1982.00340160063015

• The phagocytic activity of the bone marrow monocytes and macrophages was studied in 22 patients with sarcoidosis, 28 patients with Hodgkin's and non-Hodgkin's malignant neoplasms, and 14 controls. Although phagocytosis of RBCs and WBCs and platelets was seen in all bone marrow specimens, the activity was considerably increased in some patients with stage I and stage II sarcoidosis. This observation may reflect the presence of an unusual host response to unknown antigens in patients with sarcoidosis.

(Arch Intern Med 1982;142:479-480)