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March 1982

Flucytosine-Miconazole Treatment of Candida Peritonitis: Its Use During Continuous Ambulatory Peritoneal Dialysis

Author Affiliations

From the Nephrology Section, Department of Medicine, West Virginia University Medical Center, Morgantown, WVa (Dr Lempert); and the Infectious Diseases Section, Department of Medicine, William S. Middleton Memorial Veterans Hospital and the University of Wisconsin Medical School, Madison (Dr Jones).

Arch Intern Med. 1982;142(3):577-578. doi:10.1001/archinte.1982.00340160157028

• A case of Candida parapsilosis peritonitis occurred in a patient undergoing continuous ambulatory peritoneal dialysis (CAPD). Treatment with oral doses of flucytosine and intravenous doses of miconazole was effective. No interruption in CAPD was necessary, and acceptable flucytosine levels were obtained in the serum and dialysate. This case and information available in the literature suggest that Candida peritonitis can be treated effectively with antimicrobial agents that are well tolerated by the patient, and removal of the dialysis catheter is not always necessary for cure.

(Arch Intern Med 1982;142:577-578)

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