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April 1982

Cardiac Preload, Afterload, and Heart Failure

Author Affiliations

From the Departments of Physiology and Medicine (Dr R. C. Little), Medical College of Georgia, Augusta; and Department of Medicine, Division of Cardiology, University of Texas Health Science Center, San Antonio (Dr W. C. Little).

Arch Intern Med. 1982;142(4):819-822. doi:10.1001/archinte.1982.00340170179027

The performance of the heart is regulated by the level of myocardial contractility and the cardiac preload and afterload. These factors, previously of interest primarily to basic scientists, are now clinically important for an understanding of both cardiac function and therapeutics. In this brief review, the essence of these concepts is summarized and related to the treatment of cardiac failure.

(Arch Intern Med 1982;142:819-822)