[Skip to Navigation]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address 35.170.64.36. Please contact the publisher to request reinstatement.
Article
April 1982

Combined Vitamin D Parathyroid Defect in Thalassemia Major

Author Affiliations

From the Department of Medicine, Nassau Hospital, Mineola, NY (Drs Aloia and Yeh); Mercy Hospital, Rockville Center, NY (Dr Zaino); and the Health Sciences Center State University of New York at Stony Brook (Drs Aloia, Yeh, and Ostuni).

Arch Intern Med. 1982;142(4):831-832. doi:10.1001/archinte.1982.00340170191029
Abstract

A 17-year-old girl with thalassemia major experienced tetany. The serum calcium level was 5.5 mg/dL, and the phosphorus level was 6.3 mg/dL. Serum levels of parathyroid hormone (PTH) and 25-hydroxyvitamin D (25-OHD) were subnormal at 125 pg/mL and 8.1 ng/mL, respectively. As a result of these findings, serum 25-OHD and PTH levels were measured in an additional 12 patients with thalassemia major. Low levels of both 25-OHD and PTH were found frequently. An increase in serum 25-OHD levels was noted in each of four patients who were examined after iron chelation therapy.

(Arch Intern Med 1982;142:831-832)

×