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May 1982

Early Discharge Following Acute Myocardial Infarction: Long-term Follow-up of Randomized Patients

Author Affiliations

From the Cardiac Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston (Drs Baughman, Hutter, and DeSanctis), and the Division of Cardiology (Biostatistics), The Johns Hopkins University, Baltimore (Dr Kallman).

Arch Intern Med. 1982;142(5):875-878. doi:10.1001/archinte.1982.00340180033007

Long-term follow-up was obtained on 138 patients who participated in a prospective, randomized study comparing two weeks with three weeks of hospitalization following uncomplicated acute myocardial infarction. Follow-up information was available on 123 (89%) of all randomized patients. The mean follow-up period was 35 months for those patients who died and 99 months for those who survived. No differences were found between the two groups with respect to survival, cardiac-related deaths, frequency or severity of angina pectoris, subsequent myocardial infarction, incidence of congestive heart failure, number of ventricular aneurysms, or subsequent medical therapy. A significantly greater number of survivors in both groups stopped smoking and had a normal initial heart size than those who died. This long-term follow-up study further supports the conclusions of earlier short-term studies that two weeks of hospitalization is safe in patients with uncomplicated acute myocardial infarction.

(Arch Intern Med 1982;142:875-878)

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