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June 1982

Ankylosing Spondylitis and Systemic Lupus Erythematosus: A Rare HLA Combination

Author Affiliations

From the Rheumatology Section (Dr Nashel) and Department of Pathology (Dr Guccion), Veterans Administration Medical Center, Washington, DC; Division of Rheumatic Diseases, Georgetown University Medical Center, Washington, DC (Drs Leonard and Sliwinski); Division of Cancer Biology, National Institutes of Health, Bethesda, Md (Dr Mann); and Department of Medicine, University of Oklahoma Tulsa Medical Center (Dr Katz).

Arch Intern Med. 1982;142(6):1227-1228. doi:10.1001/archinte.1982.00340190183031

• The condition of a 43-year-old man fulfilled the strict diagnostic criteria for both ankylosing spondylitis and systemic lupus erythematosus. To our knowledge, this is the first verified report of the concurrence of these rheumatic diseases. An unusual combination of genetically determined markers seems to have caused an increased risk for the development of both disorders.

(Arch Intern Med 1982;142:1227-1228)

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