Polyarteritis nodosa developed in one of 34 patients undergoing long-term maintenance hemodialysis with persistent hepatitis B surface antigenemia. Exacerbation of the baseline hypertension and progressive peripheral neuropathy during the recovery phase of hepatitis B surface antigen hepatitis were the initial features. Poor response to aggressive corticosteroid and immunosuppressive therapy in this patient was in contrast to recent experience in patients undergoing long-term hemodialysis and the general population.
(Arch Intern Med 1982;142:1554-1556)
Gehr MK, Chopra S, Chung TJ, Hamburger RJ. Polyarteritis Nodosa After HBsAg Hepatitis in a Patient Undergoing Hemodialysis: Manifestation and Response to Therapy. Arch Intern Med. 1982;142(8):1554–1556. doi:10.1001/archinte.1982.00340210152027
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