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December 1983

Pathogenicity of Eikenella corrodens in Humans

Author Affiliations

From the Infectious Disease Section, Medical Service (Drs Suwanagool, Rothkopf, LeBlanc, and Eng), and Microbiology Section, Laboratory Service (Dr Smith), Veterans Administration Medical Center, East Orange, NJ; Infectious Disease Service, Department of Medicine, Saint Michael's Medical Center (Dr Suwanagool) and Infectious Disease Division, Department of Medicine, University of Medicine and Dentistry of New Jersey (Drs LeBlanc and Eng), Newark.

Arch Intern Med. 1983;143(12):2265-2268. doi:10.1001/archinte.1983.00350120055014

• Eikenella corrodens is resident flora of the normal adult human oral cavity. Four cases of verified infection and previous case reports of infections caused by this organism were reviewed and analyzed. Rarely has this bacillus been found as the sole isolate to initiate infection in the host with normal immune status. In the immunocompromised host, this organism was observed as the sole isolate in cases of persistent empyemas and/or overwhelming pneumonias with bacteremias. The potential of the organism singly to perpetuate an established infection appears real. In the immunocompromised patients such potentials are accentuated and can result in fulminant pulmonary infections and death. The finding of E corrodens in an infection site of a compromised patient should indicate specific therapy.

(Arch Intern Med 1983;143:2265-2268)

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