• A patient had a parathyroid adenoma and prolactin-secreting pituitary tumor, suggestive of the multiple endocrine neoplasia (MEN) I syndrome. The presence of a marfanoid habitus—found more typically in MEN III syndrome—as well as mitral valve prolapse, mental retardation, and bilateral optic atrophy suggests a new variant of the MEN syndrome, possibly representing widespread dysplasia of endocrine and other tissues.
(Arch Intern Med 1983;143:2315-2316)
Gordon S. Manning, Kenneth A. Stevens, John L. Stock. Multiple Endocrine Neoplasia, Type IAssociation With Marfanoid Habitus, Optic Atrophy, and Other Abnormalities. Arch Intern Med. 1983;143(12):2315–2316. doi:10.1001/archinte.1983.00350120109023