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April 1984

Thrombotic Thrombocytopenic Purpura-Reply

Author Affiliations

Kansas City, Mo

Winston-Salem, NC

Arch Intern Med. 1984;144(4):869. doi:10.1001/archinte.1984.00350160239054

In Reply.  —Gutterman and Stevenson raise the question of our patient having had DIC instead of TTP. Their concern about the coagulation studies needs further clarification.The prothrombin time of 13.5 s was believed to be normal (patient's control, 12.5 s). The elevated fibrinogin degradation products has been documented in TTP.1-3 Thrombocytopenia is considered to be one of the characteristic features of TTP. The second PTT (59 s) was elevated, but subsequent PTTs were normal. Abnormal coagulation studies have been seen in conjunction with TTP.3 Also the postmortem examination revealed characteristic hyaline thrombi of TTP in the ar

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