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May 1984

Urine Uric Acid and Urine Creatinine Ratio in Acute Renal Failure

Author Affiliations

From the Department of Medicine, Chulalongkorn Hospital Medical School, Bangkok, Thailand.

Arch Intern Med. 1984;144(5):934-937. doi:10.1001/archinte.1984.00350170070012

• The urine uric acid (UUA) and urine creatinine (UC) concentration ratio was studied in 23 patients with acute renal failure. The ratio was higher than 1 in 12 patients and lower than 1in 11. The clinical characteristics of the first group of patients Included the association of Infectious disease with high fever, hyperbilirubinemia, nonoliguric renal failure, less reduction of creatinine clearance, and higher urinary excretion of uric acid when compared with the second group. Jaundice and perhaps overproduction of uric acid due to hypercatabolism are believed to be responsible for the high uric acid excretion and the high UUA-UC ratio.

(Arch Intern Med 1984;144:934-937)